
Dermatology Research
GHK-Cu
Copper(II)-binding glycyl-L-histidyl-L-lysine complex
GHK-Cu is a copper-coordinated complex of the tripeptide glycyl-L-histidyl-L-lysine. It is investigated in laboratory dermatology, extracellular-matrix, metal-binding, cell-signaling, and peptide-complex characterization studies. This material is supplied solely as a research reagent for controlled laboratory use. Not for human or veterinary use.
Frequently researched together
Other laboratory research compounds available in our catalog.
Compound information
Technical specifications
What is GHK-Cu?
GHK-Cu is a synthetic 3-residue peptide complex whose sequence corresponds to glycyl-L-histidyl-L-lysine, a human tripeptide, supplied as its copper(II) coordination complex. The copper ion is held by the peptide rather than present as a simple mixed salt, so the material behaves as a metal complex in both spectroscopic and chromatographic terms. The catalogue files it under dermatology research and lists Copper tripeptide-1 as a synonym.
The sequence is Gly-His-Lys, written GHK, with the histidine imidazole side chain and the backbone nitrogens supplying the donor atoms that bind the divalent metal. The catalogue entry lists the molecular formula C14H21CuN6O4 and a molecular weight of 400.90 g/mol, a figure that describes the complex rather than the free tripeptide; a CAS registry number is not recorded in this entry. Presentation is a 100 mg vial of lyophilized material.
Lyophilized material is held at -20 C protected from light, and reconstituted solution at 2 to 8 C for short-term laboratory use, with repeated freeze-thaw cycling avoided. Purity and identity are verified by third-party HPLC and mass spectrometry, with a certificate of analysis per lot. The complex has been the subject of published laboratory and preclinical research. It is supplied strictly for laboratory research and is not for human or veterinary use.
- Molecular formula
- C14H21CuN6O4
- Molecular weight
- 400.90 g/mol
Stability information
Recommended handling and storage conditions for retaining compound identity and integrity in the laboratory.
Lyophilized
-20°C · Protect from light
Reconstituted
2-8°C
Regulatory information
Development origin and regulatory status, compiled for reference.
Research compound · Not FDA-approved
Frequently asked
Questions about GHK-Cu
What purity is GHK-Cu supplied at, and is a Certificate of Analysis available?
Yes. Each lot of GHK-Cu is tested by a third-party laboratory using HPLC for purity, and the certificate of analysis for the current lot is linked on this page and in the certificate library.
How is the identity of GHK-Cu verified?
Identity is confirmed by mass spectrometry against the expected molecular weight of 400.90 g/mol, alongside HPLC retention behaviour. Both results are recorded on the lot certificate.
How should GHK-Cu be stored on receipt?
Lyophilized: -20°C (Protect from light); Reconstituted: 2-8°C.
Where is GHK-Cu shipped from?
Orders ship from the United States in discreet, tracked packaging. Shipping is available to US addresses only.
Is GHK-Cu supplied for research use only?
Yes. GHK-Cu is sold strictly as a laboratory research material. It is not for human or veterinary use, not for diagnostic procedures, and has not been evaluated by the U.S. Food and Drug Administration. See the research use disclaimer for the full terms.
Answers describe how this material is tested, stored and shipped. They are not guidance on any use, and this compound is not for human or veterinary use.
Sources & references
Published literature in which this compound has been the subject of laboratory or preclinical study. Listed for bibliographic reference only.
Research and educational purposes only. These references are provided for bibliographic context. They are not evidence of safety or efficacy, and nothing here is medical advice or a claim about any use in humans or animals.
BioMed Research International
GHK peptide as a natural modulator of multiple cellular pathways
International journal of molecular sciences
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
BioImpacts : BI
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective
Journal of biomaterials science. Polymer edition
The human tri-peptide GHK and tissue remodeling
Oxidative medicine and cellular longevity
The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health






