Ipamorelin

Ipamorelin is a synthetic 5-residue peptide, a designed pentapeptide rather than a fragment of any natural protein, studied as a ligand for the ghrelin receptor, also called the growth hormone secretagogue receptor. The catalogue files it under cell biology, records no synonyms and supplies it as a lyophilized powder in a 10 mg vial.

The sequence is written Aib-His-D-2-Nal-D-Phe-Lys-NH2. Aib is 2-aminoisobutyric acid, a non-natural residue that constrains the backbone; D-2-Nal and D-Phe are D-configured aromatic residues, the mirror images of the natural L forms; and the C-terminal NH2 denotes an amide rather than a free acid. It is catalogued under CAS 170851-70-4 with the molecular formula C38H49N9O5 and a molecular weight of 711.90 g/mol. The formula contains no sulfur, consistent with a sequence carrying neither cysteine nor methionine, and that molecular weight is the expected mass used in identity testing.

Lyophilized material is held at -20 C protected from light, and reconstituted solution at 2 to 8 C for short-term laboratory use, with repeated freeze-thaw cycling avoided. Purity and identity are verified by third-party HPLC and mass spectrometry, with a certificate of analysis per lot. The peptide has been the subject of published laboratory and preclinical research. It is supplied strictly for laboratory research and is not for human or veterinary use.