Cell Biology
Tesamorelin(TESA)
Synthetic growth-hormone-releasing hormone analog for laboratory research
Tesamorelin is a synthetic 44-amino-acid analog of human growth-hormone-releasing hormone studied in receptor signaling, endocrine-cell response, and peptide-structure research. Not for human or veterinary use.
Frequently researched together
Other laboratory research compounds available in our catalog.
Compound information
Technical specifications
What is Tesamorelin(TESA)?
Tesamorelin is a synthetic 44-residue peptide whose sequence corresponds to human growth-hormone-releasing hormone, the hypothalamic releasing factor that acts at the GHRH receptor. It is an analogue of that hormone rather than a copy of it, prepared synthetically and supplied as a lyophilized powder in a 10 mg vial. The catalogue files the entry under cell biology, abbreviates it TESA on the label, and records no additional synonyms.
It is catalogued under CAS 218949-48-5 with the molecular formula C221H366N72O67S and a molecular weight of 5136.00 g/mol. The formula contains a single sulfur atom, so the chain carries one sulfur-bearing residue and no intrachain disulfide bridge is possible. No sequence is stated here, because the full 44-residue sequence is not recorded in the catalogue entry. At this size, electrospray mass spectrometry produces a multiply charged envelope that is deconvoluted to give the measured mass.
Lyophilized material is held at -20 C protected from light, and reconstituted solution at 2 to 8 C for short-term laboratory use, with repeated freeze-thaw cycling avoided. Purity and identity are verified by third-party HPLC and mass spectrometry, with a certificate of analysis per lot. This material is supplied strictly for laboratory research and is not for human or veterinary use.
- CAS number
- 218949-48-5
- Molecular formula
- C221H366N72O67S
- Molecular weight
- 5136.00 g/mol
Stability information
Recommended handling and storage conditions for retaining compound identity and integrity in the laboratory.
Store lyophilized at −20°C, protected from light. Reconstitute and refrigerate (2–8°C) for short-term research use.
Regulatory information
Development origin and regulatory status, compiled for reference.
Research compound · Not FDA-approved
Frequently asked
Questions about Tesamorelin(TESA)
What purity is Tesamorelin(TESA) supplied at, and is a Certificate of Analysis available?
Yes. Each lot of Tesamorelin(TESA) is tested by a third-party laboratory using HPLC for purity, and the certificate of analysis for the current lot is linked on this page and in the certificate library.
How is the identity of Tesamorelin(TESA) verified?
Identity is confirmed by mass spectrometry against the expected molecular weight of 5136.00 g/mol, alongside HPLC retention behaviour. Both results are recorded on the lot certificate.
How should Tesamorelin(TESA) be stored on receipt?
Lyophilized material is stored at -20 C protected from light. Once reconstituted it is kept at 2 to 8 C for short-term laboratory use, and repeated freeze-thaw cycles are avoided.
Where is Tesamorelin(TESA) shipped from?
Orders ship from the United States in discreet, tracked packaging. Shipping is available to US addresses only.
Is Tesamorelin(TESA) supplied for research use only?
Yes. Tesamorelin(TESA) is sold strictly as a laboratory research material. It is not for human or veterinary use, not for diagnostic procedures, and has not been evaluated by the U.S. Food and Drug Administration. See the research use disclaimer for the full terms.
Answers describe how this material is tested, stored and shipped. They are not guidance on any use, and this compound is not for human or veterinary use.
Sources & references
Published literature in which this compound has been the subject of laboratory or preclinical study. Listed for bibliographic reference only.
Research and educational purposes only. These references are provided for bibliographic context. They are not evidence of safety or efficacy, and nothing here is medical advice or a claim about any use in humans or animals.
Expert opinion on investigational drugs
Tesamorelin, a human growth hormone releasing factor analogue
Basic & clinical pharmacology & toxicology
Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue